1,2-Dichloroethane → 10-Hydroxy-10-(3-methoxy-2-methylpropyl)-2,3,4,10-tetrahydropyrimido[1,2-a]indole

HRID 305409Notes

Reaction equation

[Br:1][CH2:2][CH:3]([CH2:4][O:5][CH3:6])[CH3:7].[Cl-:23].[Cl:25][CH2:26][CH2:27][Cl:28].[Mg:8].[N:9]1=[C:14]2[N:13]([CH2:12][CH2:11][CH2:10]1)[c:21]1[c:16]([cH:17][cH:18][cH:19][cH:20]1)[C:15]2=[O:22].[NH4+:24]>>[CH2:2]([CH:3]([CH2:4][O:5][CH3:6])[CH3:7])[C:15]1([OH:22])[C:14]2=[N:9][CH2:10][CH2:11][CH2:12][N:13]2[c:21]2[c:16]1[cH:17][cH:18][cH:19][cH:20]2

Participants

Reactant 6

HCID 111,2-Dichloroethane

HCID 223Ammonium

HCID 312Chloride

HCID 5462224Magnesium

HCID 141813833,4-Dihydropyrimido(1,2-a)indol-10(2h)-one

HCID 212848141-Bromo-3-methoxy-2-methylpropane

Product 1

HCID 1418140110-Hydroxy-10-(3-methoxy-2-methylpropyl)-2,3,4,10-tetrahydropyrimido[1,2-a]indole

Sources & evidence

ORD record: ord-f9fbf41f15e648968b52b772a3f7c89e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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