Hydrochloric Acid → 1-(4-Trifluoromethoxyphenyl)-1,2,3,4-tetrahydro-isoquinoline
Reaction equation
[CH2:1]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[NH2:9].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[ClH:24].[F:10][C:11]([O:12][c:13]1[cH:14][cH:15][c:16]([C:17]([OH:18])=[O:19])[cH:20][cH:21]1)([F:22])[F:23].[OH2:25]>>[CH2:1]1[CH2:2][c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[CH:17]([c:16]2[cH:15][cH:14][c:13]([O:12][C:11]([F:10])([F:22])[F:23])[cH:21][cH:20]2)[NH:9]1Participants
6
Sources & evidence
- ORD record
- ord-a57d24770f884265a7e9520716c35083
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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