Tetrahydrofuran → 3-(5-Bromopyridin-3-ylethynyl)-benzonitrile
Reaction equation
[Br:24][c:25]1[cH:26][n:27][cH:28][c:29]([Br:30])[cH:31]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH3:32][Si:33]([CH3:34])([CH3:35])[C:36]#[C:37][c:38]1[cH:39][c:40]([C:41]#[N:42])[cH:43][cH:44][cH:45]1.[Cu:87][I:88].[F-:1].[O:19]1[CH2:20][CH2:21][CH2:22][CH2:23]1.[Pd:46]([Cl:47])[Cl:48].[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1.[c:68]1([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[cH:82][cH:83][cH:84][cH:85][cH:86]1>>[c:25]1([C:36]#[C:37][c:38]2[cH:39][c:40]([C:41]#[N:42])[cH:43][cH:44][cH:45]2)[cH:26][n:27][cH:28][c:29]([Br:30])[cH:31]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e4f7f67f967e4d76ab883e9516b26757
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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