Tetrahydrofuran → (2'-Fluoro-5'-(methyloxy)-2-(1-piperidinylmethyl)-1,1'-biphenyl-4-yl)methanol
Reaction equation
[Al+3:2].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:38][CH2:39][O:40][C:41]([CH3:42])=[O:43].[F:7][c:8]1[c:9](-[c:16]2[c:17]([CH2:26][N:27]3[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[cH:18][c:19]([C:22](=[O:23])[O:24][CH3:25])[cH:20][cH:21]2)[cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[F:7][c:8]1[c:9](-[c:16]2[c:17]([CH2:26][N:27]3[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[cH:18][c:19]([CH2:22][OH:23])[cH:20][cH:21]2)[cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3c4c461564b14876a109cb161162b380
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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