Hydrochloric Acid → 6,7-Difluoro-5-hydroxy-2-methylbenzofuran-4-carbaldehyde

HRID 310714Notes

Reaction equation

HRID 310714 reaction equation
[C:28]([O:29][CH3:30])([CH3:31])([CH3:32])[CH3:33].[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[ClH:22].[F:1][c:2]1[c:3]([F:21])[c:4]2[c:5]([cH:6][c:7]([CH3:9])[o:8]2)[c:10]([CH:19]=[O:20])[c:11]1[O:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH3:18]>>[F:1][c:2]1[c:3]([F:21])[c:4]2[c:5]([cH:6][c:7]([CH3:9])[o:8]2)[c:10]([CH:19]=[O:20])[c:11]1[OH:12]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 15413tert-Butyl methyl etherHCID 592152636,7-Difluoro-5-(2-methoxyethoxymethoxy)-2-methylbenzofuran-4-carbaldehyde

Product 1

HCID 592152776,7-Difluoro-5-hydroxy-2-methylbenzofuran-4-carbaldehyde

Sources & evidence

ORD record
ord-855f4957bc984ee8bba6bd489b01432a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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