4-Aminopyridine → 2,4,6-trichloro-N-(pyridin-4-yl)benzamide

HRID 310978Notes

Reaction equation

[CH:44]([N:45]([CH2:46][CH3:47])[CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7]([Cl:12])[cH:8][c:9]([Cl:11])[cH:10]1.[NH2:13][c:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[P-:20]([F:21])([F:22])([F:23])([F:24])([F:25])[F:26].[n:27]1([O:28][C:29]([N:30]([CH3:31])[CH3:32])=[N+:33]([CH3:34])[CH3:35])[c:36]2[n:37][cH:38][cH:39][cH:40][c:41]2[n:42][n:43]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:13][c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[c:7]([Cl:12])[cH:8][c:9]([Cl:11])[cH:10]1

Participants

Reactant 6

HCID 17274-Aminopyridine

HCID 57642,4,6-Trichlorobenzoic acid

HCID 6228Dimethylformamide

HCID 9886Hexafluorophosphate

HCID 81531Diisopropylethylamine

HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 596185842,4,6-trichloro-N-(pyridin-4-yl)benzamide

Sources & evidence

ORD record: ord-3bffe99dbd9e465980194b1772f1bf3b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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