Bromide ion → 1-(2-(2-((5-ethoxy-2-fluoro-3-isopropoxyphenyl)(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)methyl)-1-trityl-1H-imidazol-4-yl)phenyl)propan-1-ol
Reaction equation
[Br-:61].[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([O:57][CH:58]([CH3:59])[CH3:60])[c:7]([F:56])[c:8]([CH:10]([c:11]2[n:12]([C:24]([c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)([c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[cH:13][c:14](-[c:16]3[c:17]([CH:18]=[O:19])[cH:20][cH:21][cH:22][cH:23]3)[n:15]2)[NH:43][c:44]2[cH:45][cH:46][c:47](-[c:50]3[n:51][o:52][c:53]([CH3:55])[n:54]3)[cH:48][cH:49]2)[cH:9]1.[CH2:62]([CH3:63])[Mg+:64].[CH2:73]1[O:74][CH2:75][CH2:76][CH2:77]1.[CH3:65][CH2:66][O:67][C:68]([CH3:69])=[O:70].[Cl-:71].[Na+:72]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([O:57][CH:58]([CH3:59])[CH3:60])[c:7]([F:56])[c:8]([CH:10]([c:11]2[n:12]([C:24]([c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)([c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[cH:13][c:14](-[c:16]3[c:17]([CH:18]([OH:19])[CH2:62][CH3:63])[cH:20][cH:21][cH:22][cH:23]3)[n:15]2)[NH:43][c:44]2[cH:45][cH:46][c:47](-[c:50]3[n:51][o:52][c:53]([CH3:55])[n:54]3)[cH:48][cH:49]2)[cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9388795441bb4fd686d0dbad40059b3a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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