Tetrahydrofuran → 2,3-dihydro-6-(2-trimethylsilylethynyl)-(4H)-1-benzothiopyran-4-one

HRID 312260Notes

Reaction equation

HRID 312260 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[C:7](=[O:11])[CH2:8][CH2:9][S:10]2.[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH3:13][Si:14]([CH3:15])([CH3:16])[C:17]#[CH:18].[Cu:24][I:25]>>[c:2]1([C:18]#[C:17][Si:14]([CH3:13])([CH3:15])[CH3:16])[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[C:7](=[O:11])[CH2:8][CH2:9][S:10]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 139537366-Bromo-2,3-dihydro-4H-1-benzothiopyran-4-one

Product 1

HCID 154909942,3-dihydro-6-(2-trimethylsilylethynyl)-(4H)-1-benzothiopyran-4-one

Sources & evidence

ORD record
ord-995eb55fb79941bfa0c9bac2fe89ad34
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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