Chloride → 5-Chloro-2-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)pyridine

HRID 313286Notes

Reaction equation

HRID 313286 reaction equation
[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH3:32][CH2:33][O:34][CH2:35][CH3:36].[CH3:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[Cl-:31].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1.[Cl:20][Si:21]([CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[Cl:27])([CH3:28])[CH3:29].[Na+:30].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[Si:21]([CH3:28])([CH3:29])[CH2:22][CH2:23][Si:24]2([CH3:25])[CH3:26])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 312ChlorideHCID 923Sodium ionHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 8058HexaneHCID 661742-Amino-5-chloropyridineHCID 835521,2-Bis(chlorodimethylsilyl)ethaneHCID 178418339Butyllithium

Product 1

HCID 587342665-Chloro-2-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)pyridine

Sources & evidence

ORD record
ord-299f99fb6a004cf7b7569056010c2cf9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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