Trifluoroacetic acid → 5-Amino-7-chloro-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine

HRID 313398Notes

Reaction equation

HRID 313398 reaction equation
[CH3:36][O:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[Cl:1][c:2]1[cH:3][c:4]2[n:5]([c:6]([NH:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([O:14][CH3:15])[c:16]([O:17][CH3:18])[cH:19]3)[n:7]1)[n:20][c:21](-[c:23]1[o:24][cH:25][cH:26][cH:27]1)[n:22]2.[OH:28][S:29]([C:30]([F:31])([F:32])[F:33])(=[O:34])=[O:35].[OH:44][C:45]([C:46]([F:47])([F:48])[F:49])=[O:50]>>[Cl:1][c:2]1[cH:3][c:4]2[n:5]([c:6]([NH2:8])[n:7]1)[n:20][c:21](-[c:23]1[o:24][cH:25][cH:26][cH:27]1)[n:22]2

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 62406Trifluoromethanesulfonic acidHCID 155243237-Chloro-5-(3,4-dimethoxybenzylamino)-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine

Product 1

HCID 99427675-Amino-7-chloro-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine

Sources & evidence

ORD record
ord-8a5724cb55fd40c6985776eb3477f446
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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