1,2-Dichloroethane → 8-(2-Chloronicotinoylcarbamoyl)-3-isopropyl-4-methylene-2-oxo-1-oxa-3,8-diazaspiro[4,5]decane
Reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH:24]([CH3:25])([CH3:26])[N:27]1[C:28](=[O:38])[O:29][C:30]2([C:31]1=[CH2:32])[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2.[Cl:1][C:2](=[O:3])[C:4]([Cl:5])=[O:6].[Cl:39][CH2:40][CH2:41][Cl:42].[Cl:7][c:8]1[c:9]([C:10](=[O:11])[NH2:12])[cH:13][cH:14][cH:15][n:16]1>>[C:2](=[O:3])([NH:12][C:10]([c:9]1[c:8]([Cl:7])[n:16][cH:15][cH:14][cH:13]1)=[O:11])[N:35]1[CH2:34][CH2:33][C:30]2([O:29][C:28](=[O:38])[N:27]([CH:24]([CH3:25])[CH3:26])[C:31]2=[CH2:32])[CH2:37][CH2:36]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b8d7d12e5ac0419389d8e0d9101b7837
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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