Tetrahydrofuran → 4-(5-(Difluoromethoxy)-2-(6-methoxypyridin-3-ylamino)pyridin-3-YL)-N,N-bis(4-methoxybenzyl)-6-methyl-1,3,5-triazin-2-amine
Reaction equation
[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:47][Si:48]([N-:49][Si:50]([CH3:51])([CH3:52])[CH3:53])([CH3:54])[CH3:55].[F:1][CH:2]([O:3][c:4]1[cH:5][c:6](-[c:11]2[n:12][c:13]([N:18]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[CH2:28][c:29]3[cH:30][cH:31][c:32]([O:35][CH3:36])[cH:33][cH:34]3)[n:14][c:15]([CH3:17])[n:16]2)[c:7]([F:10])[n:8][cH:9]1)[F:37].[Li+:56].[NH2:38][c:39]1[cH:40][cH:41][c:42]([O:45][CH3:46])[n:43][cH:44]1>>[F:1][CH:2]([O:3][c:4]1[cH:5][c:6](-[c:11]2[n:12][c:13]([N:18]([CH2:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[CH2:28][c:29]3[cH:30][cH:31][c:32]([O:35][CH3:36])[cH:33][cH:34]3)[n:14][c:15]([CH3:17])[n:16]2)[c:7]([NH:38][c:39]2[cH:40][cH:41][c:42]([O:45][CH3:46])[n:43][cH:44]2)[n:8][cH:9]1)[F:37]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5596ac254b474096870d1feed0ce2c03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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