Phosphonic acid → Tert-butyl 2-[[1-cyano-2-[4-(4-cyano-3-fluorophenyl)phenyl]ethyl]carbamoyl]piperidine-1-carboxylate
Reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH:16]([C:21](=[O:22])[OH:23])[CH2:17][CH2:18][CH2:19][CH2:20]1.[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:5][CH2:6][CH3:7].[NH2:24][CH:25]([CH2:26][c:27]1[cH:28][cH:29][c:30](-[c:33]2[cH:34][c:35]([F:41])[c:36]([C:39]#[N:40])[cH:37][cH:38]2)[cH:31][cH:32]1)[C:42]#[N:43].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH2:56].[PH:1]([OH:2])([OH:3])=[O:4]>>[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH:16]([C:21](=[O:23])[NH:24][CH:25]([CH2:26][c:27]2[cH:28][cH:29][c:30](-[c:33]3[cH:34][c:35]([F:41])[c:36]([C:39]#[N:40])[cH:37][cH:38]3)[cH:31][cH:32]2)[C:42]#[N:43])[CH2:17][CH2:18][CH2:19][CH2:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5f2e579fbd1b440e88e063b0b93233ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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