1,2-Dichloroethane → N-(piperidin-1-yl)-4-{4-[3-(1H-pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}benzamide

HRID 318152Notes

Reaction equation

HRID 318152 reaction equation
[CH2:49]([Cl:50])[CH2:51][Cl:52].[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[ClH:53].[NH2:32][N:33]1[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]1.[O:59]1[CH2:60][CH2:61][O:62][CH2:63][CH2:64]1.[OH:39][c:40]1[c:41]2[n:42][n:43][nH:44][c:45]2[cH:46][cH:47][cH:48]1.[nH:1]1[n:2][cH:3][c:4]([CH:6]2[CH2:7][N:8]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([c:23]4[cH:24][cH:25][c:26]([C:27](=[O:28])[OH:29])[cH:30][cH:31]4)[c:17]4[cH:18][cH:19][cH:20][cH:21][c:22]43)[CH2:9][CH2:10]2)[cH:5]1>>[nH:1]1[n:2][cH:3][c:4]([CH:6]2[CH2:7][N:8]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([c:23]4[cH:24][cH:25][c:26]([C:27](=[O:29])[NH:32][N:33]5[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]5)[cH:30][cH:31]4)[c:17]4[cH:18][cH:19][cH:20][cH:21][c:22]43)[CH2:9][CH2:10]2)[cH:5]1

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 166581-AminopiperidineHCID 312751,4-DioxaneHCID 67189619HCID 67189619, compoundHCID 178418300HCID 178418300, compound

Product 1

HCID 24853022N-(piperidin-1-yl)-4-{4-[3-(1H-pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}benzamide

Sources & evidence

ORD record
ord-2a3eb1b68efd4a9090d7c7316f9ac40d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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