Diisopropylamine → HCID 18616496, compound

HRID 318855Notes

Reaction equation

HRID 318855 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][C:2]1([CH3:10])[NH:3][C:4](=[O:9])[O:5][CH:6]1[C:7]#[CH:8].[CH:23]([NH:24][CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Cl:11][c:12]1[n:13][cH:14][n:15][c:16]2[cH:17][cH:18][c:19]([I:22])[cH:20][c:21]12.[Cu:76]([I:77])[I:78].[Pd:35]([Cl:36])[Cl:37].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1.[c:57]1([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[cH:71][cH:72][cH:73][cH:74][cH:75]1>>[CH3:1][C:2]1([CH3:10])[NH:3][C:4](=[O:9])[O:5][CH:6]1[C:7]#[C:8][c:19]1[cH:18][cH:17][c:16]2[n:15][cH:14][n:13][c:12]([Cl:11])[c:21]2[cH:20]1

Participants

8

Reactant 7

HCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 83717Copper iodideHCID 111738094-Chloro-6-iodoquinazolineHCID 18616463HCID 18616463, compound

Product 1

HCID 18616496HCID 18616496, compound

Sources & evidence

ORD record
ord-5f1c404dc97548a68a09a5f7c3badeac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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