2-Pyrazinecarboxylic acid → Pyrazine-2-carboxylic acid [3-(6-methanesulfonylaminocarbonyl-3,3-dimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-amide

HRID 318866Notes

Reaction equation

HRID 318866 reaction equation
[C:10]([n:11]1[cH:12][cH:13][n:14][cH:15]1)([n:16]1[cH:17][cH:18][n:19][cH:20]1)=[O:21].[CH3:48][N:49]([CH3:50])[CH:51]=[O:52].[NH2:22][c:23]1[cH:24][c:25]([CH:29]2[NH:30][c:31]3[cH:32][cH:33][c:34]([C:41](=[O:42])[NH:43][S:44](=[O:45])(=[O:46])[CH3:47])[cH:35][c:36]3[CH2:37][C:38]2([CH3:39])[CH3:40])[cH:26][cH:27][cH:28]1.[n:1]1[c:2]([C:7](=[O:8])[OH:9])[cH:3][n:4][cH:5][cH:6]1>>[n:1]1[c:2]([C:7](=[O:9])[NH:22][c:23]2[cH:24][c:25]([CH:29]3[NH:30][c:31]4[cH:32][cH:33][c:34]([C:41](=[O:42])[NH:43][S:44](=[O:45])(=[O:46])[CH3:47])[cH:35][c:36]4[CH2:37][C:38]3([CH3:39])[CH3:40])[cH:26][cH:27][cH:28]2)[cH:3][n:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 10472-Pyrazinecarboxylic acidHCID 6228DimethylformamideHCID 682631,1'-CarbonyldiimidazoleHCID 67440482N-[2-(3-Amino-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carbonyl]-methanesulfonamide

Product 1

HCID 53492449Pyrazine-2-carboxylic acid [3-(6-methanesulfonylaminocarbonyl-3,3-dimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-amide

Sources & evidence

ORD record
ord-7932f26d605f4068aa7b5f9589c4d38d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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