Hydrochloric Acid → 2-Cyclopentyl-3-oxa-1-azaspiro[4.5]dec-1-en-4-one

HRID 320015Notes

Reaction equation

HRID 320015 reaction equation
[CH2:26]([N:27]=[C:28]=[N:29][CH2:30][CH2:31][CH2:32][N:33]([CH3:34])[CH3:35])[CH3:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH:1]1([C:6](=[O:7])[Cl:8])[CH2:2][CH2:3][CH2:4][CH2:5]1.[ClH:25].[NH2:9][C:10]1([C:16](=[O:17])[OH:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]1.[Na+:19].[Na+:20].[O-:21][C:22](=[O:23])[O-:24].[OH2:43]>>[CH:1]1([C:6]2=[N:9][C:10]3([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]3)[C:16](=[O:17])[O:7]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 962WaterHCID 13661-Aminocyclohexanecarboxylic acidHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 19660Carbonate IonHCID 78284Cyclopentanecarbonyl chloride

Product 1

HCID 247401222-Cyclopentyl-3-oxa-1-azaspiro[4.5]dec-1-en-4-one

Sources & evidence

ORD record
ord-f6a81bd7ce26427e84332fc045f885cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…