Toluene → 1-(4-(6,7-Dimethoxyquinolin-4-yloxy)-3-fluorophenyl)-4-(phenoxymethyl)pyrrolidin-2-one
Reaction equation
[CH3:38][N:39]([c:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1)[CH3:46].[CH3:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[CH3:54][CH2:55][O:56][C:57]([CH3:58])=[O:59].[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[F:16][c:17]1[cH:18][c:19]([N:24]2[C:25](=[O:37])[CH2:26][CH:27]([CH2:29][O:30][c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[CH2:28]2)[cH:20][cH:21][c:22]1[OH:23]>>[c:2]1([O:23][c:22]2[c:17]([F:16])[cH:18][c:19]([N:24]3[C:25](=[O:37])[CH2:26][CH:27]([CH2:29][O:30][c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[CH2:28]3)[cH:20][cH:21]2)[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c7e044b0f10741f1934f623e8f5e4862
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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