Potassium Cation → 4-Cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide

HRID 320329Notes

Reaction equation

HRID 320329 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:9]2=[CH:10][CH2:11][C:12]([CH3:15])([CH3:16])[CH2:13][CH2:14]2)[c:5]([NH2:8])[cH:6][cH:7]1.[C:18](#[N:19])[c:20]1[n:21][c:22]([C:33](=[O:34])[O-:35])[n:23]([CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[cH:24]1.[CH3:45][CH2:46][O:47][C:48]([CH3:49])=[O:50].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[K+:17].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[Br:1][c:2]1[cH:3][c:4]([C:9]2=[CH:10][CH2:11][C:12]([CH3:15])([CH3:16])[CH2:13][CH2:14]2)[c:5]([NH:8][C:33]([c:22]2[n:21][c:20]([C:18]#[N:19])[cH:24][n:23]2[CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])=[O:34])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 591285714-Bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenylamineHCID 591285844-Cyano-1-(2-trimethylsilylethoxymethyl)imidazole-2-carboxylate

Product 1

HCID 594575344-Cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid [4-bromo-2-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-amide

Sources & evidence

ORD record
ord-172214c8caac4c458ab355382feaed3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…