Dimethylformamide → 7-Methyl-5-(4-methyl-piperazine-1-carbonyl)-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([C:24](=[O:25])[OH:26])[cH:5][c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([F:21])([F:22])[F:23])[cH:17][cH:18]1)[CH2:7]2.[CH3:27][N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[CH3:34][CH2:35][N:36]=[C:37]=[N:38][CH2:39][CH2:40][CH2:41][N:42]([CH3:43])[CH3:44].[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[OH:45][n:46]1[c:47]2[c:48]([cH:49][cH:50][cH:51][cH:52]2)[n:53][n:54]1>>[CH3:1][c:2]1[cH:3][c:4]([C:24](=[O:26])[N:31]2[CH2:30][CH2:29][N:28]([CH3:27])[CH2:33][CH2:32]2)[cH:5][c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([F:21])([F:22])[F:23])[cH:17][cH:18]1)[CH2:7]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6347dd1018324a8b8581d4de04183a54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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