反应详情

A mixture of 4-hydroxyacetophenone (30 g), potassium carbonate (33.4 g), potassium iodide (1 g) and benzyl bromide (41.4 g) in methyl ethyl ketone (500 mL) is heated at reflux for 18 hours. The cooled reaction mixture is filtered and the filtrate evaporated. The residue is crystallised from cyclohexane to give 4-benzyloxyacetophenone (45 g, 90%).

1. temperatureis heated
2. temperatureat reflux for 18 hours
3. customThe cooled reaction mixture
4. filtrationis filtered
5. customthe filtrate evaporated
6. customThe residue is crystallised from cyclohexane