Oxalyl chloride → HCID 54563767, compound

HRID 324488Notes

Reaction equation

HRID 324488 reaction equation
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[Cl:7][C:8]1[S:9][C:10]([CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=2)=C(C(O)=O)[N:12]=1>ClCCl.CN(C)C=O>[Cl:7][C:8]1[S:9][C:10]([CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=2)=[C:1]([C:2]([Cl:4])=[O:3])[N:12]=1

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 22003631HCID 22003631, compound

Product 1

HCID 54563767HCID 54563767, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 6344DichloromethaneSolvent

Procedure

Oxalyl chloride (1.75 ml) was added to a solution of the product from step (iii) (3.14 g) in dichloromethane (30 ml) at room temperature containing 2 drops of dimethylformamide. After 4 h the volatiles were removed under reduced pressure to leave the subtitle product. Used directly in the next step.

Workup

  1. customAfter 4 h the volatiles were removed under reduced pressure

Sources & evidence

ORD record
ord-704ed9495367406ebc74b36a35c6bbb5
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

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