Methyl chloroformate → HCID 21442879, compound

HRID 328575Notes

Reaction equation

HRID 328575 reaction equation
C(N(CC)CC)C.[C:8]([C:11]1[CH:20]=[C:19]([N+:21]([O-:23])=[O:22])[C:18]([OH:24])=[C:17]2[C:12]=1[CH:13]=[CH:14][CH:15]=[N:16]2)(=[O:10])[CH3:9].[CH3:25][O:26][C:27](Cl)=[O:28]>O1CCCC1>[C:8]([C:11]1[CH:20]=[C:19]([N+:21]([O-:23])=[O:22])[C:18]([O:24][C:27]([O:26][CH3:25])=[O:28])=[C:17]2[C:12]=1[CH:13]=[CH:14][CH:15]=[N:16]2)(=[O:10])[CH3:9]

Participants

5

Reactant 3

HCID 6586Methyl chloroformateHCID 8471TriethylamineHCID 214428861-(8-Hydroxy-7-nitroquinolin-5-yl)ethan-1-one

Product 1

HCID 21442879HCID 21442879, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

10.5 g of triethylamine are added to a solution of 23 g of 5-acetyl-7-nitro-8-hydroxyquinoline in 150 ml of tetrahydrofurane and 9.5 g of chloroformic acid methyl ester are slowly added dropwise to this mixture.

Workup

  1. additionare slowly added dropwise to this mixture

Sources & evidence

ORD record
ord-601db3236799463c9bad2d54e2d3f9e7
Source dataset
uspto-grants-1977_04
Patent number
US04017627

Reaction notes

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