Ethanol → HCID 21440148, compound

HRID 328948Notes

Reaction equation

HRID 328948 reaction equation
[C:1]([C:9]1C([N+]([O-])=O)=CC(C(OCC)=O)=CC=1O)(=O)[C:2]1C=CC=C[CH:3]=1.C(I)C.[OH:27][C:28]1[CH:29]=[C:30]([CH:36]=[C:37]([N+:48]([O-:50])=[O:49])[C:38]=1[C:39](=[O:47])[C:40]1[CH:45]=[CH:44][C:43]([CH3:46])=[CH:42][CH:41]=1)[C:31]([O:33]CC)=[O:32].C(I)CCC.C(O)C>>[CH2:9]([O:27][C:28]1[CH:29]=[C:30]([CH:36]=[C:37]([N+:48]([O-:50])=[O:49])[C:38]=1[C:39](=[O:47])[C:40]1[CH:45]=[CH:44][C:43]([CH3:46])=[CH:42][CH:41]=1)[C:31]([OH:33])=[O:32])[CH2:1][CH2:2][CH3:3]

Participants

6

Reactant 5

HCID 702EthanolHCID 6340IodoethaneHCID 10962Butyl iodideHCID 21440132HCID 21440132, compoundHCID 21440165HCID 21440165, compound

Product 1

HCID 21440148HCID 21440148, compound

Procedure

By replacing in Example 6, step B, ethyl 4-benzoyl3-hydroxy-5-nitrobenzoate and ethyl iodide with equimolar amounts of ethyl 3-hydroxy-4-(4'-methylbenzoyl)-5-nitrobenzoate and n-butyl iodide respectively and following the procedure described, 3-n-butoxy-4-(4'-methylbenzoyl)5-nitrobenzoic acid crystallizing with 0.5mole of ethanol is obtained with a melting point of 162.5°-163° C.

Sources & evidence

ORD record
ord-1571820823a243b9b2ad7b53c1059800
Source dataset
uspto-grants-1977_04
Patent number
US04018794

Reaction notes

Loading…