Nitrogen → HCID 22494465, compound

HRID 344012Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.F[C:10]1[CH:24]=[CH:23][C:13]([C:14]([C:16]2[CH:21]=[CH:20][C:19](F)=[CH:18][CH:17]=2)=[O:15])=[CH:12][CH:11]=1.[C:25]([O-:28])([O-])=O.[K+].[K+].N#N>C1(C)C=CC=CC=1.CC(N(C)C)=O>[Br:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][CH:7]=1)[O:8][C:10]1[CH:24]=[CH:23][C:13]([C:14]([C:16]2[CH:21]=[CH:20][C:19]([O:28][C:25]3[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=3)=[CH:18][CH:17]=2)=[O:15])=[CH:12][CH:11]=1

Participants

Conditions

Temperature: 160 °C

Procedure

A reaction mixture was prepared with 3.8 g (22 mmol) of m-bromophenol, 2.18 g (10 mmol) of 4,4'-difluorobenzophenone, 10 ml of dimethylacetamide (DMAc), 15 ml of toluene and 4.55 g of K2CO3, and reacted at 130° C. for 1 hour while N2 gas was passed into the mixture. Subsequently, the reaction temperature was raised to 160° C. to remove toluene and water in the reaction vessel as an azeotropic mixture, and the reaction was continued for 2 hours to obtain 5.25 g of 4,4'-bis(3-bromophenoxy) benzophenone. The yield was approximately 100%.

Workup

customto remove toluene and water in the reaction vessel as an azeotropic mixture

Sources & evidence

ORD record: ord-fc795afeeb4f4707900d0dbec4396fdd
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864050

Reaction notes

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