反应详情

温度

50 °C

To a solution of 3-chloro-5-[4-(methoxymethoxy)-phenyl]-1-(4-methoxyphenyl)-1H-pyrazole obtained by Example 21 (2.35 g) in tetrahydrofuran (10 ml) and methanol (10 ml) was added 36% hydrochloric acid (0.34 ml) . The reaction mixture was stirred at room temperature for 1 hr, at 50° C. for 1.5 hrs, and at 60° C. for 1.5 hrs.

1. waitat 60° C. for 1.5 hrs