Oxygen → HCID 15501140, compound
Reaction equation
[C:1]([O:5]C)(=[O:4])C=C.[CH3:7][CH:8](O)CCCCCC.ON1[C:21](=[O:22])[C:20]2=[CH:23][CH:24]=[CH:25][CH:26]=[C:19]2[C:18]1=O.O=O>C([O-])(=O)C.[Co+2].C([O-])(=O)C.C(#N)C>[CH2:26]([C:19]1([CH3:18])[O:5][C:1](=[O:4])[CH:21]([OH:22])[CH2:20]1)[CH2:25][CH2:24][CH2:23][CH2:7][CH3:8]Participants
7
Reactant 4
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of 3 mmol of methyl acrylate, 15 mmol of 2-octanol, 0.6 mmol of N-hydroxyphthalimide, 0.003 mmol of cobalt(II) acetate, and 0.03 mmol of acetylacetonatocobalt(III), and 1 ml of acetonitrile was stirred at 50° C. in an oxygen atmosphere (1 atm) for 8 hours. A reaction mixture was subjected to column chromatography on a silica gel to yield γ-hexyl-α-hydroxy-γ-methyl-γ-butyrolactone in a yield of 74%.
Sources & evidence
- ORD record
- ord-75c9ebafe95c45fd89962df52e69bb12
- Source dataset
- uspto-grants-2007_02
- Patent number
- US07183423B1
Reaction notes
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