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HRID352357

反应详情

EQUATION

反应方程式

HRID 352357 的结构方程式

REACTANTS

反应物

2
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：COc1cc2c(cc1N1C[C@@H](C)N(C)[C@@H](C)C1)N(C(C)=O)CC2
HCID69663924

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc2c(cc1N1C[C@@H](C)N(C)[C@@H](C)C1)NCC2
HCID69836129

未命名化合物

收率 101.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cl
溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

A stirred solution of D2 (1.6 g, 5 mmole) in 2M HCl acid (50 ml) was heated under reflux for 2 h, then the solution was allowed to cool, basified with K2CO3 and extracted with DCM. The extract was dried (Na2SO4) and concentrated under vacuum to afford the title compound as a pale orange solid (1.4 g, 100%).

WORKUP

后处理

  1. temperatureunder reflux for 2 h
  2. temperatureto cool
  3. extractionextracted with DCM
  4. dry with materialThe extract was dried (Na2SO4)
  5. concentrationconcentrated under vacuum