Diethanolamine → HCID 23513849, compound

HRID 353524Notes

Reaction equation

HRID 353524 reaction equation
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].Br[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]#[N:17])=[CH:12][CH:11]=1>>[OH:4][CH2:3][CH2:2][N:1]([CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]#[N:17])=[CH:12][CH:11]=1)[CH2:5][CH2:6][OH:7]

Participants

3

Reactant 2

HCID 8113DiethanolamineHCID 869964-(Bromomethyl)benzonitrile

Product 1

HCID 23513849HCID 23513849, compound

Procedure

4-{[Bis-(2-hydroxyethyl)-amino]-methyl}benzonitrile was prepared according to the general method as outlined in Example 1 (Step 4) starting from diethanolamine (10.2 g, 97 mmol) and α-bromo-p-tolunitrile (15.8 g, 81 mmol). Yield, (68%); white solid; mp 163° C. MS: 221.2 (M+H)+.

Workup

  1. customYield

Sources & evidence

ORD record
ord-877c7931cd1943078bac2094a3ad81fc
Source dataset
uspto-grants-2004_06
Patent number
US06753337B2

Reaction notes

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