Ethyl Bromide → HCID 178477469, compound

HRID 356642Notes

Reaction equation

HRID 356642 reaction equation
[C:1]1([NH:7][C:8](=[NH:10])[SH:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:11](Br)[CH3:12].C(OC(=O)C)C>C(O)C>[CH2:11]([S:9][C:8](=[NH:10])[NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH3:12]

Participants

5

Reactant 3

HCID 6332Ethyl Bromide2×HCID 8857Ethyl AcetateHCID 178514160HCID 178514160, compound

Product 1

HCID 178477469HCID 178477469, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4 gram N-phenylisothiourea (33 mmol) and 5 ml ethyl bromide were refluxed for 10 hours in ethanol. Again 5 ml ethyl bromide was added. The reaction course was followed by thin layer chromatography (ethylacetate/petroleumether 3:7). Subsequently the solvent was evaporated and the residue crystallised from ethanol/ethylacetate.

Workup

  1. customSubsequently the solvent was evaporated
  2. customthe residue crystallised from ethanol/ethylacetate

Sources & evidence

ORD record
ord-9f8b5cebd00640a1859fa440c4f3e2d6
Source dataset
uspto-grants-1998_11
Patent number
US05837718

Reaction notes

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