反应详情

A mixture of 3-hydroxy-4-methoxybenzaldehyde (20.0 g), anhydrous potassium carbonate (26.2 g) and 2-bromopropane (18.3 mL) in dry dimethylformamide (300 mL) is stirred and heated at 55°-65° C. for 24 hours. The cooled mixture is poured into water and extracted with ethyl acetate. The extract is dried over magnesium sulfate and concentrated in vacuo at 40° C., to give 4-methoxy-3-prop-2-yloxybenzaldehyde, in the form of an oil (24.2 g).

1. temperatureheated at 55°-65° C. for 24 hours
2. extractionextracted with ethyl acetate
3. dry with materialThe extract is dried over magnesium sulfate
4. concentrationconcentrated in vacuo at 40° C.