Butyl iodide → HCID 10374661, compound

HRID 359345Notes

Reaction equation

HRID 359345 reaction equation

[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=[O:7].[H-].[Na+].[CH2:10](I)[CH2:11][CH2:12][CH3:13]>CN(C=O)C>[CH2:10]([N:1]1[CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=[O:7])[CH2:11][CH2:12][CH3:13]

Participants

5

Reactant 3

HCID 10962Butyl iodide

HCID 126652-Piperidone

HCID 24758Sodium hydride

Product 1

HCID 10374661HCID 10374661, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-Piperidinone is deprotonated with NaH in DMF solution and butylated with n-butyl iodide to give the title compound.

Sources & evidence

ORD record: ord-3d22f40af87b485387ad8bc6751cf18c
Source dataset: uspto-grants-1991_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05001113

Reaction notes

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