反应详情

In a manner similar to Scheme I, 26 (2.08 g, 7.17 mmol) was treated with the LDA-derived anion of ethylidenecyclohexylamine (1.36 g, 10.8 mmol) in anhydrous THF at 0°-5° C. and after workup and purification by SiO2 using 6:1 hexanes:EtOAc as eluent provided 1.25 g of orange solid.

1. customat 0°-5° C.
2. customafter workup and purification by SiO2 using 6:1 hexanes