Oxalyl chloride → HCID 23293624, compound

HRID 362824Notes

Reaction equation

HRID 362824 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:11]\[C:12]([OH:14])=O.C(Cl)(=O)C([Cl:18])=O>CN(C)C=O.ClCCl>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:11]\[C:12]([Cl:18])=[O:14]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 23293654HCID 23293654, compound

Product 1

HCID 23293624HCID 23293624, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneCatalystHCID 6228DimethylformamideSolvent

Procedure

A suspension of (E)-2-(4-chloro-1-indanylidene)acetic acid (5.5 g, 0.03 mol) in a mixture of dimethylformamide: dichloromethane (5 drops: 50 mL) was treated with oxalyl chloride (6.6 g, 0.05 mol) and allowed to stir at room temperature for 18 h. The resulting solution was concentrated in vacuo and the residue used without further purification.

Workup

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customthe residue used without further purification

Sources & evidence

ORD record
ord-1c7d343ef5e4487499a9e65b5b77fbdc
Source dataset
uspto-grants-1999_02
Patent number
US05872118

Reaction notes

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