Dimethylformamide → Homophthalic anhydride

HRID 363846Notes

Reaction equation

C(N([CH2:6][CH3:7])CC)C.CN([CH:11]=[O:12])C>>[C:11]1(=[O:12])[O:12][C:11](=[O:12])[C:7]2=[CH:6][CH:7]=[CH:6][CH:7]=[C:6]2[CH2:11]1

Participants

Reactant 2

HCID 6228Dimethylformamide

HCID 8471Triethylamine

Product 1

HCID 12801Homophthalic anhydride

Conditions

Temperature: 80 °C

Procedure

A solution of homophthalic anhydride (324 mg, 2 mmoles) and triethylamine (0.021 ml, 0.15 mmoles) is prepared in DMF (5 ml) and added to each packet. After heating at 80° C. for 16 hrs the packets are then washed with DMF (3×30 ml) and DCM (3×30 ml).

Workup

additionadded to each packet
washare then washed with DMF (3×30 ml) and DCM (3×30 ml)

Sources & evidence

ORD record: ord-42abb9285d244a48863da54a5669d20a
Source dataset: uspto-grants-1999_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05874443

Reaction notes

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