反应详情

温度

90 °C

After weighing 14.4 g (0.1 mol) of Meldrum's acid and 16.6 g (0.1 mol) of veratraldehyde to 50 ml of the mixture of formic acid and triethylamine prepared according to Example 1, the reaction mixture was heated to 90° C. during 1 hour and maintained at 90° C. for 2 hours. After cooling down to room temperature 200 ml of ice-water were added to the reaction mixture, the pH value was adjusted to 1 by adding concentrated hydrochloric acid and the mixture was let stand at 5° C. for 16 hours. After filtration the precipitate was washed 3 times on the filter and dried at 40° C. under reduced pressure.

1. customprepared
2. temperaturemaintained at 90° C. for 2 hours
3. additionwere added to the reaction mixture
4. customat 5° C.
5. customfor 16 hours
6. filtrationAfter filtration the precipitate
7. washwas washed 3 times on the
8. filtrationfilter
9. customdried at 40° C. under reduced pressure