反应详情

DPFC was prepared according to a published method of Metzger and Wilson (Biochem., 1964, Vol. 3, pp 926-931). Diphenylcarbamyl Chloride was obtained from Aldrich Chemical Co. Inc., Milwaukee, Wis., USA. DFPC was prepared from the chloride by reaction with 50% excess antimony trifluoride in hot xylene for one hour. The mixture was cooled to room temperature. Antimony halides were then precipitated with ether and the solution decolorized with charcoal, filtered and evaporated to dryness. The solids thus obtained were dissolved in Methanol, decolorized with charcoal, filtered and crystalized by cooling the solution to about 0° C. This process was repeated again and yielded white crystals with melting point of 81°-82° C.

1. customDPFC was prepared
2. customAntimony halides were then precipitated with ether
3. filtrationfiltered
4. customevaporated to dryness
5. customThe solids thus obtained
6. filtrationfiltered
7. customcrystalized
8. temperatureby cooling the solution to about 0° C
9. customyielded white crystals with melting point of 81°-82° C.