Hydrochloric Acid → HCID 70351092, compound

HRID 365131Notes

Reaction equation

HRID 365131 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=O.[C:13]1([CH2:19][C:20]([OH:22])=[O:21])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C(OC(=O)C)(=O)C.Cl>C(N(CC)CC)C>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[C:19]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:20]([OH:22])=[O:21]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 999Phenylacetic AcidHCID 62012-NaphthalenecarboxaldehydeHCID 7918Acetic Anhydride

Product 1

HCID 70351092HCID 70351092, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

A mixture of 2-naphthaldehyde (5 g, 32 mmole), phenylacetic acid (4.4 g, 32 mmole), triethylamine (5 mL) and acetic anhydride (10 mL) were refluxed for 5 hours. The solution was poured into 2N HCl (150 mL) and a precipitate formed immediately. This was recrystallized from 50% aqueous ethanol to yield 7.8 g (89% yield) of a white power.

Workup

  1. temperaturewere refluxed for 5 hours
  2. customa precipitate formed immediately
  3. customThis was recrystallized from 50% aqueous ethanol
  4. customto yield 7.8 g (89% yield) of a white power

Sources & evidence

ORD record
ord-7f1bab22fbe74b7c8ed8b2240e7d36a3
Source dataset
uspto-grants-1986_08
Patent number
US04608390

Reaction notes

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