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HRID366782

反应详情

EQUATION

反应方程式

HRID 366782 的结构方程式

REACTANTS

反应物

5
结构：CN1CCOCC1
HCID7972

4-Methylmorpholine

C5H11NO

结构：On1nnc2ccccc21
HCID75771

1-Hydroxybenzotriazole

C6H5N3O

结构：Cl.O=C(O)Cc1ccncc1
HCID81097

4-Carboxymethylpyridinium chloride

C7H8ClNO2

结构：CCN=C=NCCCN(C)C.Cl
HCID2723939

1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride

C8H18ClN3

结构：Clc1ccc2c(c1)OCc1cccnc1C2=C1CCNCC1
HCID15780498

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3OCc3cccnc32)CC1
HCID9824087

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The title compound was prepared according to the method of Example 4 from 4-(8-chloro-5,11-dihydro[1]benzoxepino[4,3-b]pyridin-11-ylidene)-piperidine, 4-pyridine-acetic acid hydrochloride, HOBT, EDCl and NMM in DMF. 4-(8-Chloro-5,11-dihydro[1]benz-oxepino[4,3-b]pyridin-11-ylidene)-1-(4-pyridine-acetyl)piperidine was obtained as a white foam; MS (CI, M+H)=432; anal.: found: C, 68.71; H, 5.44; N, 9.44; C25H22ClN3O2 requires: C, 69.52; H, 5.13; N, 9.73.

WORKUP

后处理

  1. customThe title compound was prepared