反应详情

To a solution of 2.34 g of 4-allylthio-3-ethylazetidinone in 20 ml of redistilled dimethylformamide were added 1.37 ml of methyl bromoacetate and 4.16 g of ground potassium carbonate. The solution was stirred overnight then filtered through a pad of Hyflo, (Hyflo being a Trade Mark), poured into 75 ml of water, and extracted five times with ethyl acetate. The combined organic extracts were washed with water, dried over magnesium sulphate, and evaporated in vacuo to give the title compound. (Yield 3 g)

1. filtrationthen filtered through a pad of Hyflo
2. additionpoured into 75 ml of water
3. extractionextracted five times with ethyl acetate
4. washThe combined organic extracts were washed with water
5. dry with materialdried over magnesium sulphate
6. customevaporated in vacuo