Potassium Carbonate → HCID 21472340, compound

HRID 37215Notes

Reaction equation

HRID 37215 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:15])[C:9]#[C:10][CH2:11][CH2:12][CH2:13][CH3:14])=[CH:4][CH:3]=1.[CH3:16]C1C=C(C)C=C(C)C=1S([O-])(=O)=O.[NH2:29][N+:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1C.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:9]2[C:31]([CH2:32][CH2:33][CH2:34][CH3:35])=[N:30][N:29]3[C:14]([CH3:16])=[CH:13][CH:12]=[CH:11][C:10]=23)=[O:15])=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 12022872HCID 12022872, compoundHCID 544491361-(4-Bromophenyl) 2-heptyn-1-one

Product 1

HCID 21472340HCID 21472340, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 11.4 g of the product of Stage A of Example 1, 250 ml of dimethylformamide and 9.81 g of 1-amino 2-methylpyridinium 2,4,6-trimethyl-benzene sulfonate (Synthesis, 1977, page 1, TAMURA, et al.) and 5.11 g of potassium carbonate were stirred for 5 hours at ambient temperature.

Sources & evidence

ORD record
ord-0bc925d40dea443fb918fe585560b973
Source dataset
uspto-grants-1995_05
Patent number
US05420138

Reaction notes

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