反应详情

The free base was prepared from the hydrochloride (from Example 19) by dissolving the hydrochloride in water (15 mL/2 g of hydrochloride) and adding saturated aqueous sodium bicarbonate until the pH exceeded 8. After stirring for 15 minutes, the precipitate was collected, washed with water and dried to give the desired product.

1. customthe precipitate was collected
2. washwashed with water
3. customdried