反应详情

A mixture of 2-chloro-5-(fluorosulfonyl)benzoic acid (11.93 g, 0.05 mol), diethylamine (10.97 g, 0.15 mol) and 1,2-dichloroethane (100 mL) was refluxed for 8 hours. The reaction mixture was evaporated and the residue was dissolved in ethyl acetate. A solid was collected by filtration and the filtrate was evaporated to dryness to afford 15.5 g of 2-chloro-5-diethylaminosulfonyl)benzoic acid.

1. temperaturewas refluxed for 8 hours
2. customThe reaction mixture was evaporated
3. dissolutionthe residue was dissolved in ethyl acetate
4. filtrationA solid was collected by filtration
5. customthe filtrate was evaporated to dryness