Isopropanol → HCID 19359693, compound

HRID 376830Notes

Reaction equation

HRID 376830 reaction equation
[Na].Cl[Sn:3](Cl)(Cl)[CH2:4][CH2:5][CH2:6][NH2:7].[CH:10]([OH:13])([CH3:12])[CH3:11]>>[CH3:11][CH:10]([CH3:12])[O-:13].[CH3:11][CH:10]([CH3:12])[O-:13].[CH3:11][CH:10]([CH3:12])[O-:13].[NH2:7][CH2:6][CH2:5][CH2:4][Sn+3:3]

Participants

4

Reactant 3

HCID 3776Isopropanol2×HCID 5360545Sodium2×HCID 19359899HCID 19359899, compound

Product 1

HCID 19359693HCID 19359693, compoundYield 59%

Conditions

Temperature
70 °C

Procedure

0.57 g of sodium (0.025 mol) was treated with 80 ml of isopropylalcohol in a 200 ml eggplant type flask and the mixture was heated at 60° C. until sodium was completely dissolved. To this solution 50 ml of an isopropylalcohol solution containing the 3-(trichlorostannyl)propylamine (4.9 mmol), prepared in the aforementioned example (4), was added dropwise at a room temperature. Subsequently, the mixture was stirred while heating for 6 hours at 70° C. The resultant supernatant was separated and concentrated under reduced pressure to yield 2.4 g of the final product of 3-aminopropyltin tris(methylethoxide) (yield=59%).

Workup

  1. dissolutionwas completely dissolved
  2. customprepared in the aforementioned example (4)
  3. additionwas added dropwise at a room temperature
  4. customThe resultant supernatant was separated
  5. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-61992c4da5674c509248738421b232b7
Source dataset
uspto-grants-2000_02
Patent number
US06022822

Reaction notes

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