反应详情

Prepared according to the method described in Example 1a) from diethylazodicarboxylate (6.7 ml), triphenylphosphine (13.11 g), (R)-(+)-ethyl lactate (5.67 ml) and 4-bromophenol (8.65 g) in dry tetrahydrofuran (125 ml). The residue obtained after work-up was purified by column chromatography over silica eluting with isohexane:dichloromethane (2:3) to give the sub-title compound as an oil (12.2 g).

1. customPrepared
2. customThe residue obtained after work-up
3. customwas purified by column chromatography over silica eluting with isohexane:dichloromethane (2:3)