反应详情

Similarly, but replacing 4-(6-chloro-3,4-dihydro-2H-benzo[1,4]oxazin-8-yl)-piperazine-1-carboxylic acid tert-butyl ester with 4-(6-tert-butyl-3,4-dihydro-2H-benzo[1,4]oxazin-8-yl)-piperazine-1-carboxylic acid tert-butyl ester, and replacing 3-methylsulfonyl-benzenesulfonyl chloride with the appropriate aryl- or heteroaryl-sulfonyl chlorides followed by de-protection using trifluoracetic acid or hot hydrogen chloride in ethanol, the following was prepared:

1. customthe following was prepared