反应详情

To a solution of 3-bromo-7-methoxyquinoline 1-oxide (2.04 g, 8.03 mmol) in EtOAc (50 mL) and 15% aqueous K2CO3 (15 mL) at RT, TsCl (1.68 g, 8.83 mmol) was added. The reaction mixture was stirred vigorously at RT for 18 hours, at which time the product was collected by filtration and washed with EtOAc. The solid was dried under vacuum and used with no further purification. LRMS (M+H)+=254.1.

1. filtrationwas collected by filtration
2. washwashed with EtOAc
3. customThe solid was dried under vacuum
4. customused with no further purification