反应详情

To a solution of EXAMPLE 1C (4.6 g, 14.08 mmol) in anhydrous tetrahydrofuran (30 mL) was added benzaldehyde (0.71 mL, 7.4 mmol) and triethylamine (1.00 mL, 7.39 mmol). The reaction mixture was stirred at ambient temperature overnight. Water was added and the mixture stirred for 10 minutes. The precipitated solid was filtered and dried under vacuum to yield the title compound. MS (ESI) m/z 302 (M+H)+.

1. stirringthe mixture stirred for 10 minutes
2. filtrationThe precipitated solid was filtered
3. customdried under vacuum