Trityl chloride → HCID 15372343, compound

HRID 392684Notes

Reaction equation

HRID 392684 reaction equation
[C:1](Cl)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1.C(N(CC)CC)C>>[C:1]([N:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 6456Trityl chlorideHCID 8471TriethylamineHCID 31268Pyrrolidine

Product 1

HCID 15372343HCID 15372343, compoundYield 82.4%

Procedure

2.00 g (7.2 mmol) of trityl chloride was treated with 0.51 g (7.2 mmol) pyrrolidine and 0.72 g (7.2 mmol) triethylamine according to General Method C in Example 6 to give 1.86 g (82%) of 1-tritylpyrrolidine (T7), mp: 126° C.

Sources & evidence

ORD record
ord-1b1dbf440ad8411abd9442826f5e1c0a
Source dataset
uspto-grants-2004_10
Patent number
US06803375B1

Reaction notes

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