反应详情

温度

120 °C

Compound 10 (100 mg, 0.220 mmol), thiophenol (˜200 μL), and diisopropylethylamine (100 mL) were combined under Ar and heated at 120° C. for 3 h. The mixture was purified by flash column chromatography (hexane:ethyl acetate 70:30) to afford a foam. Crystallization from hexane:ethyl acetate afforded 59 mg (0.112 mmol, 51%) of Compound 86.

1. customThe mixture was purified by flash column chromatography (hexane:ethyl acetate 70:30)
2. customto afford a foam
3. customCrystallization from hexane